Farmington JAX is studying the genome in 3D

Three-dimensional genomic compartments and sub-compartments help regulate gene expression across the genome. As more data comes out about 3D genomic structures, there is an increasing need to efficiently identify and characterize sub-compartments and their roles in genome function.

Sheng Li and her team, based at The Jackson Laboratory facility in Farmington CT, have developed a new computational tool, SCI, that outperforms previously developed algorithms for this purpose. more