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So far Bill Kelly has created 1211 blog entries.

Loxo receives FDA ‘breakthrough’ designation

Loxo Oncology has been granted Breakthrough Therapy Designation by the U.S. Food & Drug Administration for cancer treatment drug LOXO-292. The medication is a selective rearranged during transfection (RET) inhibitor for the treatment of patients with advanced RET fusion-positive thyroid cancer who require systemic therapy, have progressed following prior treatment and have no acceptable alternative treatment options. more

By |October 26th, 2018|News|0 Comments

Norwalk Hospital collaborates re breast cancer

Norwalk Hospital, part of Western Connecticut Health Network, has launched four new breast cancer clinical trials in partnership with the New York's Memorial Sloan Kettering Cancer Center (MSK). The collaboration is overseen by oncologists from the C. Anthony and Jean Whittingham Cancer Center at Norwalk Hospital and MSK. The hospital says it is the first in Connecticut to offer the four trials. more

By |October 18th, 2018|News|0 Comments

UConn: Role of immune system in premature birth

Premature birth is the leading cause of infant death and disability in the U.S., and costs billions in dollars and heartache every year. Now, University of Connecticut researchers report a potential treatment that could stop many cases of premature labor and birth in their tracks. UConn Health’s Christopher Nold, an obstetrician who practices maternal-fetal medicine at Hartford Hospital, and Anthony Vella, an immunologist, were curious about the immune system’s role in premature birth. The researchers knew that cytokines, small proteins that alert the body to infection and cause inflammation, had been found in the amniotic fluid of many women who [...]

By |October 18th, 2018|News|0 Comments

Yale’s Nordhaus wins 2018 Nobel in Economics

William Nordhaus, Sterling Professor of Economics at Yale University and the world’s leading economist on climate change, has been awarded the 2018 Sveriges Riksbank Prize in Economic Sciences for “integrating climate change into long-run macroeconomic analysis.” Nordhaus shared the prize with Paul Romer, professor of economics at New York University’s Leonard N. Stern School of Business. more

By |October 18th, 2018|News|0 Comments

Biohaven, UConn, PITCH collaborate re antibody

Biohaven has signed an exclusive, worldwide option and license agreement with the University of Connecticut for the development and commercialization rights to UC1MT, a therapeutic antibody targeting extracellular metallothionein (MT). Extracellular MT has been implicated in the pathogenesis of autoimmune and inflammatory diseases. The antibody was discovered in the laboratory of Michael Lynes, PhD, head of the Department of Molecular & Cell Biology at the University of Connecticut Storrs. Professor Lynes worked with PITCH, a Connecticut Bioscience Innovation Fund program that cultivates innovative therapeutics conceived in Connecticut’s universities in order to grow Connecticut’s biotech ecosystem. Within PITCH, the anitbody was scaled for [...]

By |October 15th, 2018|News|0 Comments

Cybrexa appoints Keely Zipp VP of Marketing

Cybrexa Therapeutics has appointed Keely Zipp Vice President of Marketing. Ms. Zipp adds nearly 15 years of strategic planning and marketing experience to the Cybrexa team and will lead the company’s marketing, communications, and branding efforts. Cybrexa is an early-stage biotechnology company developing a new class of cancer therapeutics through its tumor-selective technology platform. more

By |October 15th, 2018|News|0 Comments

Yale team sees link between glucose and malaria

More than one million people die annually from cerebral malaria, the most lethal form of the disease. A recent study, led by Yale investigators, explores the role of glucose metabolism in the development of the disease, and may hold a key to preventing or treating it in humans. Blocking glucose metabolism with glucose inhibitor 2DG appears to help mice tolerate infection-related damage to the brain by decreasing the ability of malaria to cause the blood to clot. more

By |October 15th, 2018|News|0 Comments

BioCT Entrepreneur of the Year Award: Nominations

Nominations are being accepted through November 15 for the BioCT Entrepreneur of the Year Award - 2018.  The award winner will be announced at the BioCT Holiday Party December 11, from 5:00 pm to 7:00 pm at Alexion in New Haven. Save the date! The Entrepreneur of the Year Award was established by BioCT and Shipman and Goodwin to acknowledge the importance of showcasing unique accomplishments of entrepreneurs in the community. The award seeks to recognize individuals who are imaginative, passionate and game-changers in Connecticut bioscience and whose accomplishments would be heralded outside of Connecticut. details and nomination forms

By |October 15th, 2018|News|0 Comments

JAX wins grant re genetic role in substance abuse

The National Institute on Drug Abuse has funded a bold new approach to understanding the biology of substance abuse, with a five-year grant totaling $3,967,656 to Jackson Laboratory researchers exploring the role of the microbiome and genetics in substance use disorders. A number of genes have been associated with addiction, and there is accumulating evidence that the gut microbiome — the vast collection of microbes that inhabit the digestive tract and interact with the host — plays a significant role in behavioral response to addictive drugs, as well as anxiety- and depression-like behaviors, many of which occur with addiction. more

By |October 15th, 2018|News|0 Comments

BioCT adds Scientist.com business solution

BioCT is pleased to announce the addition of Scientist.com to our cost-saving BIO Business Solutions program - an exclusive BioCT member benefit. Scientist.com is the world’s largest marketplace for outsourced scientific services and products, to offer researchers access to a platform with thousands of pre-qualified suppliers providing custom research services. Immediate savings are realized by sending requests to multiple suppliers in a single click. Signing up is simple, and Scientist.com’s Research Concierge™ — a team comprising experts with decades of scientific experience — can assist with any order no matter how complex the project. more

By |October 15th, 2018|News|0 Comments