A new five-year federal research grant totaling $2,317,760 will fund studies by Jackson Laboratory (JAX) Assistant Professor Duygu Ucar, Ph.D., into the mechanisms that cause the immune system to decline with age.

“As we age,” Ucar says, “the immune system, which protects the body from infections and tumors, loses strength. The wide-ranging health consequences of this include increased vulnerability to bacteria such as pneumococcal pneumonia, vaccines working less well, and individuals becoming more susceptible to some cancers.”