Achillion Pharmaceuticals, Inc.

300 George Street
New Haven, CT 06511

Phone: 203-624-7000

General Information:

Achillion Pharmaceuticals is an innovative biopharmaceutical company dedicated to bringing important new treatments to patients with infectious disease.The Company’s highly skilled and experienced discovery and development teams have advanced multiple product candidates with proven mechanisms of action. Achillion is focused on solutions for the most challenging problems in infectious disease including treatments for chronic hepatitis C viral infections (HCV). Headquartered in New Haven, Connecticut, Achillion is a publicly traded company with its common stock traded on the NASDAQ Global Select Market under the symbol: ACHN.

Research Activities
Focused on HCV, Achillion is advancing a second-generation NS5A inhibitor, ACH-3102, a potent inhibitor of HCV NS5A that demonstrates pico-molar potency, pan-genotypic activity, and an enhanced resistance profile compared to first-generation NS5A inhibitors. Achillion is also advancing once-daily NS3/4A protease inhibitors including ACH-2684, a potent, second-generation compound entering Phase 2, and sovaprevir, a next-generation protease inhibitor which is currently on clinical hold by the Food and Drug Administration (FDA). Lastly, Achillion has discovered a novel nucleotide NS5B polymerase inhibitor, ACH-3422. Each of these programs was discovered through Achillion’s own proprietary internal drug discovery efforts.