The National Institutes of Health has awarded AxioMx an SBIR research grant that will be used to develop a technique for isolating antibodies against complex antigens composed of cross-linked protein-DNA complexes.

The site-specific binding of proteins to DNA, exemplified by transcription factor gene promoter complexes, plays an important role in cell development, cell signaling, the cell cycle, and diseases such as cancer, infection, and inflammation

The advent of next-generation sequencing has paved the way for chromatin immunoprecipitation sequencing, a technique that allows researchers to identify the specific DNA-binding sites at which proteins interact directly with the genome.