Evaluation of the Induction of Protective Immunity Against Pulmonary Cryptococcosis in a Humanized Immune System Mouse Model – Hosted by Taconic Biosciences

Humanized immune system (HIS) mice are critical to preclinical investigations of infectious diseases, like HIV, prior to clinical studies. Furthermore, these models can be used to study HIV/AIDS-related opportunistic diseases, such as cryptococcosis. Join us in this webinar as Dr. Floyd Wormley, a leading expert in the field of cryptococcosis infectious disease, discusses the utility of Taconic’s huNOG-EXL model to examine human pulmonary responses against attenuated strains of Cryptococcus neoformans. During this webinar, Dr. Wormley will discuss how to model the disease in the huNOG-EXL mouse in order to define protective immunity and potential human vaccine-mediated immune responses against cryptococcus infection.

Dr. Floyd Wormley is one of the leaders in the field of cryptococcosis infectious disease. His lab recently conducted a study with Taconic’s huNOG-EXL model to examine human pulmonary responses against attenuated strains of C. neoformans in order to define protective immunity and potential human vaccine-mediated immune responses.

Get insight into how Dr. Wormley modelled this infectious disease in Taconic’s huNOG-EXL, the results of his lab’s study, and considerations when selecting a humanized immune system model for your research. The webinar will be followed by a Q&A section – we encourage all to participate!

Attend this webinar to:

• Discover the potential of humanized immune system models for infectious disease applications.
• Get a better understanding of how to model infectious diseases in humanized mice.
• Hear about the latest research into cryptococcosis infection from one of the field’s leading experts.
• Explore Taconic’s humanized immune system model portfolio.

Bio:

Floyd Wormley, PhD, Associate Provost for Research, Dean of Graduate Studies at Texas Christian University

Dr. Floyd Wormley’s research focuses on development of new vaccines and therapies to prevent and treat invasive fungal infections. He received his PhD in Microbiology/Immunology from the Louisiana State University (LSU) Health Sciences Center. After completing postdoctoral training in infectious diseases at Duke University Medical Center, he joined the University of Texas, San Antonio (UTSA), where he served as assistant, associate, and full professor within the Department of Biology, before being appointed Associate Dean for Research and Graduate Studies within the College of Sciences. Currently he is the Associate Provost for Research and Dean of Graduate Studies at Texas Christian University (TCU). His research background includes microbial pathogenesis, medical mycology, host-pathogen interactions, mucosal immunology, and vaccine development.