Cybrexa Therapeutics has completed the GLP toxicology study of its lead candidate, CBX-12. The positive results for this study serve as a guide for dosing regimen for the planned Phase I trial of CBX-12 as Cybrexa intends to file the IND during the first quarter 2021.
“The successful completion of the GLP toxicology studies is an early, yet significant milestone in the development of our lead candidate CBX-12, a highly potent alphalex PDC conjugate that we believe has the potential to impact several types of solid tumors, both as a monotherapy and in combination with PD-1 inhibitors and other immuno-oncology drugs,” said Per Hellsund, President and CEO of Cybrexa.